ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] One of the neuropathological hallmarks of Alzheimer's disease is the neurofibrillary tangle, which contains paired helical filaments (PHFs) composed of the microtubule-associated protein tau,. Tau is hyperphosphorylated in PHFs,, and phosphorylation of tau abolishes its ability to bind ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/21650
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