Publication Date:
2014-09-06
Description:
Article Clozapine-induced agranulocytosis/granulocytopenia, or CIAG, is characterised by a rare and potentially fatal reaction to antipsychotic drugs. Here, the authors identify genetic variants in two immune-related genes that may contribute to the pathophysiology of CIAG. Nature Communications doi: 10.1038/ncomms5757 Authors: Jacqueline I. Goldstein, L. Fredrik Jarskog, Chris Hilliard, Ana Alfirevic, Laramie Duncan, Denis Fourches, Hailiang Huang, Monkol Lek, Benjamin M. Neale, Stephan Ripke, Kevin Shianna, Jin P. Szatkiewicz, Alexander Tropsha, Edwin JCG van den Oord, Ingolf Cascorbi, Michael Dettling, Ephraim Gazit, Donald C. Goff, Arthur L. Holden, Deanna L. Kelly, Anil K. Malhotra, Jimmi Nielsen, Munir Pirmohamed, Dan Rujescu, Thomas Werge, Deborah L. Levy, Richard C. Josiassen, James L. Kennedy, Jeffrey A. Lieberman, Mark J. Daly, Patrick F. Sullivan
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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