Publication Date:
2015-09-10
Description:
Article G-protein-coupled receptors (GPCRs) signal via G proteins or arrestin-mediated pathways; the plasticity of arrestin proteins is thought to underlie their function. Here, the authors use NMR to examine how β-arrestin-1 recognizes different GPCR phospho-barcodes, and how this triggers structural rearrangements to fulfill selective functions. Nature Communications doi: 10.1038/ncomms9202 Authors: Fan Yang, Xiao Yu, Chuan Liu, Chang-Xiu Qu, Zheng Gong, Hong-Da Liu, Fa-Hui Li, Hong-Mei Wang, Dong-Fang He, Fan Yi, Chen Song, Chang-Lin Tian, Kun-Hong Xiao, Jiang-Yun Wang, Jin-Peng Sun
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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