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    Publication Date: 2019-01-25
    Description: Lower vertebrates have been used in space research for at least 3 decades, and have a number of advantages such as the ability to be maintained safely in space conditions, high development rates, easy observability, and small size. Several major investigations with lower vertebrates are in the flight queue in various countries, and some of this research with amphibians that has Canadian Space Agency sponsorship is reviewed. In connection with NASA's frog embryology experiment, Canadian scientists will conduct postflight experiments on live tadpoles brought back from space to determine whether larvae that develop from these embryos are behaviorally normal. Swimming kinematics in particular will be examined, since a distinctive looping behavior of Xenopus tadpoles under microgravity has been noted. A collaborative study with the Institute of Biomedical Problems in Moscow is designed to elucidate the relationship between buoyancy regulation and lung development in tadpoles, and is scheduled to fly on a Biocosmos satellite in 1992.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Canadian Space Agency, Spacebound 1991; p 146-150
    Format: text
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  • 2
    Publication Date: 2019-07-13
    Description: To test whether gravity is required for normal amphibian development, Xenopus laevis females were induced to ovulate aboard the orbiting Space Shuttle. Eggs were fertilized in vitro, and although early embryonic stages showed some abnormalities, the embryos were able to regulate and produce nearly normal larvae. These results demonstrate that a vertebrate can ovulate in the virtual absence of gravity and that the eggs can develop to a free-living stage.
    Keywords: Life Sciences (General)
    Type: NASA-TM-111839 , NAS 1.15:111839 , Proc. Natl. Acad. Sci.; 92; 1975-1978
    Format: application/pdf
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