ISSN:
1432-0983
Schlagwort(e):
ATPase 9
;
Cytochrome oxidase
;
DNA nucleotide sequence
;
Intron
;
Mitochondria
;
NADH dehydrogenase
;
tRNA
;
Trichophyton rubrum
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
Notizen:
Summary In this paper, we present the nucleotide sequence of a 5248 bp-long region of the mitochondrial (mt) genome of the dermatophyte Trichophyton rubrum. This region which represents about 1/4 of the total mt genome of this species reveals a compact organization of genes including: the glutaminyl tRNA, the methionyl tRNA, the cytochrome oxidase subunit 1 gene, the arginyl tRNA, the mitochondrial version of the ATPase subunit 9 gene, the cytochrome oxidase subunit II gene and a part of the NADH dehydrogenase ND4L and ND5 gene “complex”. The main features of the part of mt DNA sequenced is the non-interrupted COXI gene and the presence in the mitochondrial version of the ATPase 9 gene of a small group IA intron. The extensive amino-acid sequence similarity with the equivalent gene in Aspergillus nidulans and neuropora crassa indicates that this gene codes for a dicyclohexylcarbodiimide binding protein. The conserved arrangement of this portion of the mt genome and the presence of tRNAs between the protein-coding genes are compatible with a large polycistronic transcript processed by the excision of tRNAs, or similar secondary structures, as proposed for other fungal or mammalian mt DNAS.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00351730
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