ISSN:
1573-5117
Keywords:
monoclonal antibodies
;
regional antigen
;
regeneration
;
pattern formation
;
immunohistochemistry
;
Dugesia (G.) tigrina
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract We have produced monoclonal antibodies (mAbs) against antigens of the freshwater planarian Dugesia (G.) tigrina (Girard) using standard protocols. One of these mAbs, TCEN-49, detects an antigen (TCEN-49Ag) present in most cells of the central area of the body, including the pharynx. Labelled cells seem more related by position than by lineage, suggesting that TCEN-49Ag is involved somehow in the expression of central body positional identity. The spatial and temporal changes in TCEN-49Ag expression during growth/degrowth and regeneration have been monitored and the implications of these results are discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00036395
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