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Linkage and polymorphism of a gene controlling lactate dehydrogenase in the rat (1983)

Stolc, V. ; Gill, T. J.

Springer

Biochemical genetics 21 (1983), S. 933-941

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ISSN: 1573-4927

Keywords: rat ; lactate dehydrogenase ; regulator

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract The amount of lactate dehydrogenase subunit A in rat serum is under the control of the lactate dehydrogenase regulatory gene Ldr-1, and it is determined by two alleles, Ldr-1 a (high) and Ldr-1 b (low). Sex and LDH-A level segregate independently, so the Ldr-1 gene is autosomal. The genes for albino, red eye, hemoglobin, and Ldr-1 are linked (linkage group I), and their order is Ldr-1-Hbb-r-c. Our data put Ldr-1 45 cM from Hbb, and Hbb is 7 cM from c. Data in the literature separate r and c by 0.3 cM.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00483951

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