ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

Hits per page

hit 1 - 1 | 1 hit

Sorting

Electronic Resource

Dissociation of insulin binding from insulin stimulation of 2-deoxyglucose transport by ruthenium red (1986)

Williams, P. F. ; Plehwe, W. E. ; Turtle, J. R.

Springer

Bioscience reports 6 (1986), S. 317-322

add to mindlist on the mindlist

Details

ISSN: 1573-4935

Keywords: Insulin binding ; insulin action ; glucose transport ; calcium ; ruthenium red

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract Ruthenium red increased specific insulin binding to isolated adipocytes 5.4 fold and 2.6 fold over binding determined in the absence and presence of Ca2+ and Mg2+. The increase in insulin binding was not accompanied by an increase in insulin sensitivity. The lack of effect of ruthenium red on insulin action argued strongly against an increase in intracellular Ca2+ as a potential messenger/transducer of insulin action and suggested that the enhancing effect of Ca2+ on insulin action was a result of increased receptor affinity.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01115161

Permalink

	Location	Call Number	Expected	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

hit 1 - 1 | 1 hit