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Hemoglobin polymorphism in inbred strains of rats (Rattus norvegicus) (1982)

Stolc, V. ; Kunz, H. W. ; Gill, T. J.

Springer

Biochemical genetics 20 (1982), S. 395-403

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ISSN: 1573-4927

Keywords: rat ; hemoglobin ; inbred strains ; mutation

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract Hemoglobin phenotypes A and B were determined by polyacrylamide gel electrophoresis of erythrocyte lysates from 29 inbred strains of rats. Fourteen strains have phenotype A and fifteen have phenotype B, which are characterized by five and six hemoglobin bands, respectively. Breeding studies showed that the phenotypes are codominant and that they segregate in a simple Mendelian fashion in the (A×B) F1×A backcross. Sex and hemoglobin phenotype assort independently, and the hemoglobin phenotype is not linked to the major histocompatibility complex (RT1) and to two erythrocyte alloantigenic systems (RT2 and RT3).

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00484433

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