ISSN:
0021-9304
Keywords:
composite materials
;
carbon fiber
;
implant
;
femoral
;
bone
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
,
Technology
Notes:
A novel composite material with an ultra-high strength and a low elastic modulus called carbon-fiber-reinforced liquid crystalline polymer (LCP/CF) has been developed. We studied the effects of an intramedullary LCP/CF rod on bone in rabbits. A LCP/CF rod of 3.2 mm in diameter and 50 mm in length was introduced into the intramedullary canal of the right femur in ten rabbits weighing an average of 3.6 (3.1-4.2) kg. The follow-up intervals were 3 and 52 weeks. No signs of deformity or osteopenia were seen in the operated femurs in the radiographic, histological, and histomorphometric studies. Histologically, the implant was enclosed by cancellous bone in the metaphyseal area and by a thin cancellous bone cuff in medullary cavity. Bone was able to grow in direct contact with the LCP/CF rod. No signs of degradation of the implants or of adverse tissue reaction were seen. The intramedullary LCP/CF rod had no harmful effects on bone in rabbits. The biocompatibility of the LCP/CF appeared to be good. This novel composite material demonstrates properties that may be useful in orthopedic applications. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res, 42, 407-411, 1998.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
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