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Effect of cyclic AMP on mitosis in the esophageal epithelium of mice with tumors (1977)

Volkov, I. N.

Springer

Bulletin of experimental biology and medicine 84 (1977), S. 1174-1176

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ISSN: 1573-8221

Keywords: esophagus ; mitosis ; mitotic cycle ; dibutyryl-cyclic 3,5-AMP

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Abstract Mitotic activity and the number of DNA-synthesizing cells were studied in the epithelium of the esophageal mucosa of albino mice with tumors during the 24 h after administration of dibutyrylcyclic 3,5-AMP. Injection of the compound leads to delay of the cells in the G2 phase of the mitotic cycle and to an increase in the duration of mitosis during the first few hours of the experiments, without changing the total number of cells passing through the mitotic cycle in the 24-h period.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00799212

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