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Threshold for inhibition of Na, K-ATPase by ELF alternating currents (1992)

Blank, Martin ; Soo, Lily

New York, NY [u.a.] : Wiley-Blackwell

Bioelectromagnetics 13 (1992), S. 329-333

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ISSN: 0197-8462

Keywords: enzyme function ; membrane protein ; ion pump ; electric field ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Physics

Notes: Alternating currents can increase or decrease the ATP-splitting activity of the membrane enzyme Na,K-ATPase. Either change depends on the AC frequency, and the greatest effect appears to be in the ELF range at about 100 Hz. The threshold for enzyme inhibition by AC was determined, and it is estimated to be an internal electric field circa 5 μV/cm. The corresponding current-density threshold approximates 8 nA/cm2. 1992 Wiley-Liss, Inc.

Additional Material: 2 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/bem.2250130409

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