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  • electrophysiology  (1)
  • long-term potentiation  (1)
  • 1
    Electronic Resource
    Electronic Resource
    4-Aminopyridine and barium chloride attenuate the anti-epileptic effect of carbamazepine in hippocampal slices (1991)
    Springer
    Cellular and molecular life sciences 47 (1991), S. 254-257 
    Details
    ISSN: 1420-9071
    Keywords: Carbamazepine ; potassium ; hippocampus ; epilepsy ; electrophysiology ; 4-aminopyridine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The exact mode of action of the anti-epileptic agent carbamazepine is unknown. In hippocampal slices in which epileptiform discharges were induced by addition of penicillin to the perfusion medium, the depressant effect of carbamazepine was attenuated by the potassium-channel blockers barium chloride (0.1 mM) and 4-aminopyridine (200 μM), which suggested that potassium fluxes might be involved in the mechanism of action of carbamazepine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01958152
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  • 2
    Electronic Resource
    Electronic Resource
    Long-term potentiation and 4-aminopyridine (1985)
    Springer
    Cellular and molecular neurobiology 5 (1985), S. 297-301 
    Details
    ISSN: 1573-6830
    Keywords: long-term potentiation ; 4-aminopyridine ; hippocampal slice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary 1. Long-term potentiation (LTP) of excitatory postsynaptic potentials (epsp's) was investigated with extracellular field potential recording in hippocampal slices from rats. 2. In the presence of 100µM 4-aminopyridine (4-AP) the probability of eliciting LTP was unchanged or increased; the extent of potentiation was not significantly different from normal. 3. During LTP saturation, 4-AP further enhanced the epsp. 4. These data are inconsistent with an involvement of A-current reduction in LTP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00711014
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    Paper (German National Licenses)
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