ISSN:
1573-904X
Keywords:
betamethasone, ocular effects: phenylephrine, ocular effects
;
polyvinyl alcohols, modulation of ocular drug effects
;
drug delivery, ocular
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The effect of different concentrations of polyvinyl alcohol 14000 and 72000 (PVA 14 and 72) on the activity of betamethasone and phenylephrine hydrochloride in the rabbit eye was investigated. The polymer of higher molecular weight exerts a more pronounced effect at relatively lower viscosities. Effects on the intraocular pressure are more responsive to changes in viscosity than those on pupillary response.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1016398915965
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