ISSN:
0886-1544
Keywords:
cilia
;
calcium
;
cAMP
;
differential response
;
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
Ciliated sheets of cell cortex were prepared from Triton-glycerol-extracted Paramecium to observe directly the change of ciliary orientation. The observation of the ciliary responses revealed the modes of ciliary control by Ca2+ and cyclic nucleotides. The cilia changed their pointing direction clockwise from 11-12 to 5 o'clock (with the anterior of the cell defined as 12 o'clock) in the horizontal plane of cell surface when Ca2+ concentration was decreased from 10-6 M to 10-7 M. Cyclic AMP competed with Ca2+ ion in determining the orientation of the cilia. On the other hand, cGMP tended to change the ciliary orientation toward 3 o'clock. Ciliary sensitivity to cyclic nucleotides depended on their location on the cell surface. The cilia on the left-hand field of the cell were more sensitive to cyclic nucleotide than those on the right-hand field. The differential distribution of ciliary sensitivity within a single cell seems to be functional in the sophisticated turning mechanism in the behavioral response of Paramecium.
Additional Material:
8 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cm.970200105
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