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Bioactive polymers XXI. Coupling of chloramphenicol on Biozan R (1985)

Simionescu, Cr. I. ; Popa, M. I. ; Dumitriu, S.

Springer

Colloid & polymer science 263 (1985), S. 620-623

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ISSN: 1435-1536

Keywords: Biozan R ; chloramphenicol ; coupling ; antimicrobial activity ; dicyclohexylcarbodiimide

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

Notes: Abstract The coupling of chloramphenicol on Biozan R (Hercules) by activation with dicyclohexylcarbodiimide was studied. The esterification is influenced by the chloramphenicol/dicyclohexylcarbodiimide ratio, concentration of the reactants and reaction time. The microbial tests performed with products of different chloramphenicol contents attest their antimicrobial activity and their possible use, especially in ophtalmology.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01419885

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