ISSN:
1573-904X
Keywords:
thrombolytic
;
tissue plasminogen activator
;
plasminogen activators
;
coronary thrombolysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Thrombolytic therapy has received renewed attention with the demonstration that early treatment of acute myocardial infarction with plasminogen activators can reduce mortality. Tissue plasminogen activator (t-PA) is a protein with attributes that may allow for greater efficacy and safety. Recombinant DNA technology has enabled the production of sufficient t-PA, called rt-PA (Activase), for substantial clinical evaluation. The results suggest that Activase is a significant advance in thrombolytic therapy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1016474026501
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