ISSN:
1573-1561
Keywords:
chemical communication
;
phenylalanine metabolism
;
guinea pig urinary metabolites
;
phenylacetaldehyde oxime
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract Domestic guinea pigs having high levels of circulating testosterone (i.e., males and castrate males receiving testosterone propionate injections) excrete in their urine equal amounts of both thesyn andanti isomers of phenylacetaldehyde oxime, while those guinea pigs having low testosterone titers (i.e., females, castrate males, and juveniles) excrete neither. These aldoximes were also detected in the urine of wild male guinea pigs. Radiolabeling studies in the domestic guinea pigs strongly suggest that these aldoximes are derived from phenylalanine. To our knowledge this is the first observation and isolation of phenylacetaldehyde oxime from a mammalian source. The significance of these components in phenylalanine metabolism as well as in guinea pig chemical communication is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00988446
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