ISSN:
1617-4623
Keywords:
Bkm DNA
;
Polymorphism
;
Wild Mouse
;
Y chromosome
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Using 32P-labeled probe consisting mainly of (GATA)n we have shown that a male specific Alu1 DNA blot pattern which defines the Y chromosome sex-determining locus in inbred mice is highly polymorphic in wild mice, indicating substantial sequence evolution in this region under field conditions. In all cases examined by in situ hybridization, the region concerned is paracentromeric. In contrast, the blot pattern of another probe (M 34) which detects repeated sequences specific to the mouse Y chromosome but outside the sex-determining locus, remains constant between different isolates.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00330848
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