ISSN:
1615-6102
Keywords:
Endoplasmic reticulum structure
;
Mitochondria
;
Cytoskeleton
;
Energy metabolism
;
Endothelial cells
;
Xenopus
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary FITC-Con A fluorescence was used to visualize rER arrangement of endothelial cells derived fromXenopus laevis tadpole hearts. In particular determinants of rER organization, intracellular localization and the interrelationships with other organelles were analysed. rER occurs in association with nucleus, mitochondria and microtubules. The structure of rER is strongly affected by energy metabolism and by microtubules. In order to elucidate the interdependence of structure and function we examined the influence of cellular respiration, net lactate production and protein synthesis on rER morphology, as well as the relationship between energy metabolism and protein synthesis. ER morphology is determined primarily by energy consuming intracellular transport mechanisms. Energy needed for protein synthesis is supplied by the respiratory chain while ATP from aerobic glycolysis only compensates when respiration is disturbed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01323274
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