Publication Date:
2001-02-24
Description:
Working out which areas of the brain become activated during the formation of working (short-term) memory has been greatly helped by functional magnetic resonance imaging (fMRI). In a Perspective, Robbins et al. discuss new findings (Furey et al.) with fMRI that reveal how working memory is enhanced by the drug physostigmine, which increases cholinergic function in the brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Robbins, T W -- Mehta, M A -- Sahakian, B J -- New York, N.Y. -- Science. 2000 Dec 22;290(5500):2275-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, UK. twr2@cus.cam.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11188728" target="_blank"〉PubMed〈/a〉
Keywords:
Acetylcholine/*physiology
;
Brain Mapping
;
Cholinesterase Inhibitors/pharmacology
;
Face
;
Humans
;
Magnetic Resonance Imaging
;
Memory, Short-Term/*drug effects
;
Pattern Recognition, Visual
;
Physostigmine/*pharmacology
;
Prefrontal Cortex/drug effects/*physiology
;
Receptors, Muscarinic/metabolism
;
Receptors, Nicotinic/metabolism
;
Tomography, Emission-Computed
;
Visual Cortex/drug effects/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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