ISSN:
1573-6849
Keywords:
Bubalus bubalis
;
chromosomes
;
FISH
;
river buffalo
;
UMPS
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Uridine monophosphate synthase plays an important role in pyrimidine synthesis, converting orotic acid to uridine 5′ monophosphate. In cattle,UMPS deficiency is inherited as a monogenic autosomal recessive trait. While heterozygous carriers are phenotypically normal, homozygotes are lethalin utero (Shankset al. 1992).UMPS has been mapped to human chromosome 3q13 (Qumsiyehet al. 1989), sheep chromosome 1q (Burkinet al. 1993) and cattle chromosome 1q31 (Ryanet al. 1994). In the present study we used a cattle genomic probe to localizeUMPS to river buffalo chromosomes by fluorescencein situ hybridization.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01553326
Permalink