ISSN:
0749-1581
Keywords:
13C NMR
;
15N NMR
;
Methanesulphonanilides
;
Substituent effects
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The 13C and 15N NMR spectra of some ortho-, meta- and para-substituted methanesulphonanilides were recorded. Correlations of the 13C chemical shifts with the appropriate substituent chemical shifts (SCS) for monosubstituted benzenes were excellent and showed enhancement of the substituent effects at C-1 (para to the substituent). The C-1 chemical shifts were also examined by means of the dual substituent parameter (DSP) and DSP-nonlinear resonance equations. The results indicate that the - NHSO2 Me moiety is a weak electron donor. The 15N chemical shifts of the para-substituted compounds were analysed by means of DSP equations and the results compared with those of related compounds. Ortho-substituted compounds indicate the high sensitivity of 15N chemical shifts towards steric compression. T1 and nuclear Overhauser enhancement data for the protonated carbons of methyl-substituted compounds are given.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260280708
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