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Granular pneumocytes and altitude: A stereological evaluation (1979)

Pearson, Anita K. ; Pearson, Oliver P.

Springer

Cell & tissue research 201 (1979), S. 137-144

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ISSN: 1432-0878

Keywords: Granular pneumocyte ; Surfactant ; Stereology ; Phyllotis darwini ; Adaptation to altitude

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary Stereological analysis demonstrates that the granular pneumocytes of mice native to high altitude (4660 m) are significantly larger than those of the same species (Phyllotis darwini) living at sea level. Such cells have larger nuclei and a significantly greater volume of mitochondria. There are both more and larger lamellar bodies in high altitude granular pneumocytes, resulting in about four times more surfactant per cell at high altitude.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00238053

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