ISSN:
1573-8221
Keywords:
yeasts
;
fungi
;
antifungal drugs
;
sensitivity
;
atopic dermatitis
;
bronchial asthma
;
bronchomycosis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Yeast microflora was studied in the skin of 91 patients with atopic dermatitis, in bronchial secretion of 13 patients with bronchial asthma and 8 patients with allergic bronchopulmonary mycosis. Forty-eight isolates were obtained. Alypophilic yeast fungi isolated from the skin were presented mainly by generaCandida spp. (48%) andRhodotorula spp. (29%), while the cultures isolated from bronchial secretion mainly byCandida albicans. The sensitivity of yeast cultures to the antifungal drugs diflucan, clotrimazole, nizoral, orungal, exoderil, levorin, pymafuzin, and nitrofungin was determined. The most efficient drugs were diflucan, clotrimazole, nizoral, and orungal. More than half isolates were sensitive only to the high concentrations of levorin (48%), pymafuzin (75%), and nitrofungin (82%); 64% isolates were insensitive even to high concentrations of exoderil. Preliminaryin vitro selection of the antifungal drugs is required for efficient elimination of the yeasts.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02434889
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