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  • Space Sciences (General)  (1)
  • antibacterial activitydithiocarbamatesdithiolium saltsflavonoidsSAR studies  (1)
  • 1
    Publication Date: 2016-05-24
    Description: A structure–activity relationship study concerning the antibacterial properties of several halogen-substituted tricyclic sulfur-containing flavonoids has been performed. The compounds have been synthesized by cyclocondensation of the corresponding 3-dithiocarbamic flavanones under acidic conditions. The influence of different halogen substituents on the antibacterial properties has been tested against Staphylococcus aureus and Escherichia coli . Amongst the N , N -dialkylamino-substituted flavonoids, those having an N , N -diethylamino moiety exhibited good to excellent antimicrobial properties against both pathogens. Fluorine-substituted flavonoids were found to be less active than those bearing other halogen atoms. Beilstein J. Org. Chem. 2016, 12, 1065–1071. doi:10.3762/bjoc.12.100
    Keywords: antibacterial activitydithiocarbamatesdithiolium saltsflavonoidsSAR studies
    Electronic ISSN: 1860-5397
    Topics: Chemistry and Pharmacology
    Published by Beilstein-Institut
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  • 2
    Publication Date: 2019-07-13
    Description: Near-Earth Asteroids (NEAs) are an easily accessible object in Earth's vicinity. Detections of NEAs are expected to grow in the near future, offering increasing target opportunities. As NASA continues to refine its plans to possibly explore these small worlds with human explorers, initial reconnaissance with comparatively inexpensive robotic precursors is necessary. Obtaining and analyzing relevant data about these bodies via robotic precursors before committing a crew to visit a NEA will significantly minimize crew and mission risk, as well as maximize exploration return potential. The Marshall Space Flight Center (MSFC) and Jet Propulsion Laboratory (JPL) are jointly examining a mission concept, tentatively called 'NEA Scout,' utilizing a low-cost CubeSats platform in response to the current needs for affordable missions with exploration science value. The NEA Scout mission concept would be a secondary payload on the Space Launch System (SLS) Exploration Mission 1 (EM-1), the first planned flight of the SLS and the second un-crewed test flight of the Orion Multi-Purpose Crew Vehicle (MPCV).
    Keywords: Space Sciences (General)
    Type: M14-3850 , AIAA Space 2014 Conference; Aug 04, 2014 - Aug 07, 2014; San Diego, CA; United States
    Format: application/pdf
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