ISSN:
0935-6304
Keywords:
Two-dimensional thin layer chromatography
;
Contour diagram
;
Continuous development
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Several methods for evaluating separation quality in two-dimensional thin layer chromatography are discussed. These include using either the distance between spot centers for the pair of solutes that is the most difficult to separate in a mixture, or the value of a suitable, separation function, as criteria of overall separation quality. Contour diagrams may be constructed in which solvent compositions for each of the two-dimensional developments are the independent variables and spot separation or the value of a suitable function is the dependent variable. Such diagrams indicate which are the best and the worst regions of the two-dimensional solvent domain. These diagrams should be of value for comparing different solvent systems for two-dimensional thin layer chromatography.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240101007
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