ISSN:
1432-0878
Schlagwort(e):
Microtubules
;
Halothane
;
Sciatic nerve (Rat)
;
Repolymerisation
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary The effect of halothane and colchicine on microtubule repolymerisation after exposure to cold has been examined in the sciatic nerve of the rat. Myelinated axons showed a significant decrease in microtubule numbers and density after exposure to both 20 mM halothane and 10−5 M colchicine; exposure to both agents simultaneously produced a further significant reduction when compared to halothane alone. It is suggested that halothane can interfere with microtubule repolymerisation in mammalian axons possibly in a similar way to that described in invertebrates.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00234841
Permalink
