ISSN:
0009-2940
Keywords:
Quinine
;
Cinchonidine
;
Quinidine
;
Chinchonine
;
Ruthenium complexes
;
Gold complexes
;
Rhodium complexes
;
Iridium complexes
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The following chiral organometallic complexes of the cinchona alkaloids quinine (L1), cinchonidine (L2), quinidine (L3), cinchonine (L4) were prepared: [(η5-C5H5)(Ph3P)(OC)-Ru(L)]BF4 (1: L=L1; 2: L=L2; 3: L=L3), ClAuL1 (4), [(η5-C5Me5)(Cl2)Ir(L)] (5: L=L1; 6: L=L2; 7: L=L4), [(η5-C5Me5)(Cl2)Rh(L2)] (8), [(η6-p-cymene)(Cl2)Ru(L)] (9: L=L1; 10: L=L2; 11: L=L4). In all complexes the tertiary nitrogen atom of the cinchona alkaloids is bound to the metal. Complexes 5 - 11 are formed as mixtures of isomers. Elimination of HCl from 10 and 11 gives the neutral N,O-chelate complexes (η6-p-cymene)(Cl)Ru(L2 - H+) (13) and (η6-p-cymene)-(Cl)Ru(L4 - H+) (14) which were structurally characterized by X-ray diffraction.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19961290314
Permalink