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  • Quantum optics, physics of lasers, nonlinear optics, classical optics  (3)
  • Rosa  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitro (1987)
    Springer
    Planta 172 (1987), S. 252-264 
    Details
    ISSN: 1432-2048
    Keywords: Dinitroaniline ; Rosa ; Herbicide ; Microtubule ; Oryzalin ; Haemanthus ; Taxol ; tubulin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The effects of oryzalin, a dinitroaniline herbicide, on chromosome behavior and on cellular microtubules (MTs) were examined by light microscopy and immunogold staining, respectively, in endosperm cells from Haemanthus katherinae Bak. Brief treatments with 1.0·10-8 M oryzalin reduced markedly the migration rate of anaphase chromosomes and 1.0·10-7 M oryzalin stopped migration abruptly. Oryzalin (1.0·10-7 M) depolymerized MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle. The chromosome condensation cycle was unaffected by oryzalin. Endothelial cells from the heart of Xenopus leavis showed no chromosomal or microtubular rearrangements after oryzalin treatment. The inhibition by oryzalin of the polymerization of tubulin isolated from cultured cells of Rosa sp. cv. Paul's scarlet was examined in vitro by turbidimetry, electron microscopy and polymer sedimentation analysis. Oryzalin inhibited the rapid phase of taxol-induced polymerization of rose MTs at 24°C with an apparent inhibition constant (K i ) of 2.59·106 M. Shorter and fewer MTs were formed with increasing oryzalin concentrations, and maximum inhibition of taxol-induced polymerization occurred at approx. 1:1 molar ratios of oryzalin and tubulin. Oryzalin partially depolymerized taxol-stabilized rose MTs. Ligand-binding experiments with [14C]oryzalin demonstrated the formation of a tubulin-oryzalin complex that was time- and pH-dependent. The tubulin-oryzalin interaction (24°C, pH 7.1) had an apparent affinity constant (K app) of 1.19·105 M-1. Oryzalin did not inhibit taxol-induced polymerization of bovinebrain MTs and no appreciable binding of oryzalin to brain tubulin or other proteins was detected. The results demonstrate pharmacological differences between plant and animal tubulins and indicate that the most sensitive mode of action of the dinitroaniline herbicides is the direct poisoning of MT dynamics in cells of higher plants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00394595
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    Paper (German National Licenses)
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  • 2
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    Tunable multiphonon blockade in coupled nanomechanical resonators (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-01-08
    Description: Author(s): Adam Miranowicz, Jiří Bajer, Neill Lambert, Yu-xi Liu, and Franco Nori A single phonon in a nonlinear nanomechanical resonator (NAMR) can block the excitation of a second phonon [ Phys. Rev. A 82 , 032101 (2010) ]. This intrinsically quantum effect is called phonon blockade, and is an analog of Coulomb blockade and photon blockade. Here we predict tunable multiphonon bloc… [Phys. Rev. A 93, 013808] Published Thu Jan 07, 2016
    Keywords: Quantum optics, physics of lasers, nonlinear optics, classical optics
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
    Published by American Physical Society (APS)
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  • 3
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    Two-photon and three-photon blockades in driven nonlinear systems (2013)
    American Physical Society (APS)
    Details
    Publication Date: 2013-02-09
    Description: Author(s): Adam Miranowicz, Małgorzata Paprzycka, Yu-xi Liu, Jiří Bajer, and Franco Nori Photon blockade, in analogy to Coulomb's or phonon blockades, is a phenomenon when a single photon in a nonlinear cavity blocks the transmission of a second photon. This effect can occur in Kerr-type systems driven by a laser due to strong nonlinear photon-photon interactions. We predict the occurre... [Phys. Rev. A 87, 023809] Published Fri Feb 08, 2013
    Keywords: Quantum optics, physics of lasers, nonlinear optics, classical optics
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
    Published by American Physical Society (APS)
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  • 4
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    State-dependent photon blockade via quantum-reservoir engineering (2014)
    American Physical Society (APS)
    Details
    Publication Date: 2014-09-20
    Description: Author(s): Adam Miranowicz, Jiří Bajer, Małgorzata Paprzycka, Yu-xi Liu, Alexandre M. Zagoskin, and Franco Nori An arbitrary initial state of an optical or microwave field in a lossy driven nonlinear cavity can be changed into a partially incoherent superposition of only the vacuum and the single-photon states. This effect is known as single-photon blockade, which is usually analyzed for a Kerr-type nonlinear... [Phys. Rev. A 90, 033831] Published Fri Sep 19, 2014
    Keywords: Quantum optics, physics of lasers, nonlinear optics, classical optics
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
    Published by American Physical Society (APS)
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