ISSN:
0570-0833
Schlagwort(e):
Michael addition
;
Pyridinium salts
;
Synthetic methods
;
Chemistry
;
General Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
By Michael addition of the active methylene groups in pyridinium salts onto suitable acceptor compounds, α-pyridones, substituted pyridines, particularly pyridinecarboxylic acids and pyridylpyridines, including the minor alkaloid of tobacco nicotelline and annelized pyridines, can be prepared by a simple procedure and generally in good yields. From the Michael adducts, polycyclic aromatic hydrocarbons, e.g. substituted fluoranthenes and “bisfluoranthenes” can be prepared; internal Michael addition leads to pyrrolinopyrdinium salts. For example, Michael addition of pyridinium salts onto quinones gives phenacyl substituted quinones, from which benzofurans and cinnolines can be readily obtained.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/anie.196206261
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