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  • Polymer and Materials Science  (2)
  • 1
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Biopolymers 16 (1977), S. 317-326 
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Intensity-fluctuation laser-light-scattering spectroscopy has been used to characterize the temperature dependence of the translational diffusion coefficient through the helix-coil region for the DNA isolated from bacteriophage N1. The diffusion coefficient does not change smoothly, but exhibits fine structure detail similar to that seen in the uv absorption hyperchromicity. These changes are related to the heterogeneous distribution of bases along the N1-DNA chain.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Biopolymers 16 (1977), S. 327-340 
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Intensity-fluctuation laser-scattering spectroscopy measurements have been reported for the DNA isolated from bacteriophage φ29. The cumulant method of data analysis gives well-defined weighted average decay frequencies. Available theoretical models are shown to yield good values for the diffusion coefficient and longest intramolecular relaxation time for low-molecular-weight DNA's but not for higher molecular weight species. The temperature dependence of the apparent diffusion coefficient exhibits drastic oscillations in the helix-coil transition region. The number of these oscillations is consistent with independent measurements of uv hyperchromicity measurements and suggests that φ29-DNA is composed of at least three regions of differing G + C content.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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