ISSN:
1434-1948
Keywords:
α-Metallated amino acids
;
Palladium
;
Platinum
;
Oxidative addition
;
α-Bromoglycinate
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Oxidative addition of methyl N-benzoyl-2-bromoglycinate to bis(dibenzylideneacetone)palladium, in the presence of 2,2′-bipyridyl, and to (Ph3P)2Pt(η2-C2H4) gives the α-metallated glycine esters 1a and 2a. Abstraction of bromide from 1a, 2a, using AgSbF6 or AgBF4, affords the cationic C,O-chelate complexes [(bpy)Pd-CH(CO2Me)NHC(Ph)O]+ (1b,c) and [(Ph3P)2Pt-CH(CO2Me)NHC(Ph)O]+ (2b), respectively, featuring coordination of the amide O atom. The complexes 1b and 2b have been characterized by X-ray diffraction.
Type of Medium:
Electronic Resource
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