Publication Date:
2001-09-08
Description:
Genetic self-incompatibility in Brassica is determined by alleles of the transmembrane serine-threonine kinase SRK, which functions in the stigma epidermis, and of the cysteine-rich peptide SCR, which functions in pollen. Using tagged versions of SRK and SCR as well as endogenous stigma and pollen proteins, we show that SCR binds the SRK ectodomain and that this binding is allele specific. Thus, SRK and SCR function as a receptor-ligand pair in the recognition of self pollen. Specificity in the self-incompatibility response derives from allele-specific formation of SRK-SCR complexes at the pollen-stigma interface.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kachroo, A -- Schopfer, C R -- Nasrallah, M E -- Nasrallah, J B -- GM57527/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2001 Sep 7;293(5536):1824-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Plant Biology, Cornell University, Ithaca, NY 14853, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11546871" target="_blank"〉PubMed〈/a〉
Keywords:
*Alleles
;
Binding Sites
;
Brassica/*genetics/*metabolism
;
Fertilization/physiology
;
Ligands
;
Plant Proteins/genetics/*metabolism
;
Plant Structures/*metabolism
;
Plants, Genetically Modified
;
Plants, Toxic
;
Pollen/*metabolism
;
Protein Binding
;
Protein Kinases/chemistry/genetics/*metabolism
;
Recombinant Fusion Proteins/genetics/metabolism
;
Species Specificity
;
Substrate Specificity
;
Tobacco
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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