ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • free radicals  (4)
  • Physicochemical Phenomena  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Interrelation of active oxygen species, membrane damage and altered calcium functions (1992)
    Springer
    Molecular and cellular biochemistry 111 (1992), S. 11-15 
    Details
    ISSN: 1573-4919
    Keywords: superoxide dismutase ; oxidative stress ; toxicology ; calcium fluxes ; free radicals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Incubation of freshly isolated rat liver mitochondria in the presence of oxygen free radical generating hypoxanthine —xanthine oxidase system led to swelling of mitochondria as measured by the change in optical density, which was reversed by the addition of superoxide dismutase. O2 − in the presence of CaCl2 enhanced the peroxidative decomposition of mitochondrial membrane lipids along with swelling of the organelle. Free radical generation led to enhancement of monoamine oxidase activity while glutathione peroxidase and cytochrome c oxidase were inhibited. Tertbutyl hydroperoxide (t-BHP) caused mitochondrial swelling through oxidative stress. Incorporation of ruthenium red, which is a Ca2+ transport blocker, during assay abolished peroxidative membrane damage and swelling. Dithiothreitol (DTT) accorded protection against t-BHP induced mitochondrial swelling. The above in vitro data suggest a possible interrelationship of active oxygen species, membrane damage and calcium dynamics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00229568
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Influence of some biological response modifiers on swelling of rat liver mitochondriain vitro (1993)
    Springer
    Molecular and cellular biochemistry 124 (1993), S. 101-106 
    Details
    ISSN: 1573-4919
    Keywords: mitochondrial swelling ; lipid peroxidation ; Ca functions ; biological response modifiers ; free radicals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract In order to understand any involvement of altered calcium functions in peroxidative membrane damage, the effect of a few chemicals, known to modify specific biological responses involving calcium related functions on mitochondrial swellingin vitro was studied. Histamine caused swelling, whereas antihistamines reduced calcium induced swelling. Anti-inflammatory agents aspirin and indomethacin did not affect the initial rapid phase of swelling but reduced the swelling during the later phase. The uncouplers of oxidative phosphorylation and electron transport chain blockers such as dinitrophenol (DNP), antimycin-A and rotenone reduced swelling and the respiratory inhibitors KCN and sodium azide completely abolished it. Trifluoperazine, an anti-calmodulin agent did not influence the initial phase of calcium induced swelling but in the subsequent phase swelling was reduced. c-AMP as well as calcium ionophores, calcimycin and lasalocid acid, potentiated swelling. Thus agents capable of modulating calcium functions could influence thein vitro swelling of mitochondria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00929201
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    tBHP induced in vitro swelling of rat liver mitochondria (1996)
    Springer
    Molecular and cellular biochemistry 154 (1996), S. 39-45 
    Details
    ISSN: 1573-4919
    Keywords: free radicals ; oxidative stress ; mitochondrial swelling ; tert-butyl hydroperoxide ; calcium deregulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Tert-butyl hydroperoxide induced swelling of freshly isolated rat liver mitochondria was inhibited by butylated hydroxytoluene, butylated hydroxyanisole and α-tocopherol by acting at the initial phase. EDTA was more effective than EGTA in reducing the initial swelling and so were desferal and bipyrridyl. Spermine, an allosteric activator of calcium uptake, enhanced swelling whereas lanthanum and ruthenium red, the Ca2+ uniport blockers, reduced it. Inhibition of phospholipase A2 by dibucaine and Ca2+ activated proteases by antipain and leupeptin also reduced t-BHP induced swelling. The data indicate that peroxidative mitochondrial swelling involves an iron mediated initial rapid phase and a subsequent calcium dependent propagation phase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00248459
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Influence of Antioxidants on the Peroxidative Swelling of Mitochondria in vitro (1998)
    Springer
    Cell biology and toxicology 14 (1998), S. 313-321 
    Details
    ISSN: 1573-6822
    Keywords: antioxidants ; free radicals ; oxidative swelling ; peroxidation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract To clarify the role of prooxidative processes during in vitro swelling of freshly isolated rat liver mitochondria, the influence of different antioxidants and free-radical scavengers was tested. Ascorbate below 10 mmol/L without externally added Fe2+ acted as a prooxidant and enhanced swelling. Higher concentrations in the presence of Fe2+ showed antioxidant properties and a decrease in swelling and lipid peroxidation. Swelling was abolished by α-tocopherol and reduced to 50% by butylated hydroxytoluene. Glutathione supplementation decreased both swelling and lipid peroxidation. Oxidized glutathione caused swelling without any effect on peroxidation. Hydrogen peroxide, cumene hydroperoxide and t-butyl hydroperoxide caused progressive decreases in glutathione and reduced niacinamide coenzyme levels, suggesting prooxidative changes. Dithiothreitol was found to abolish this effect. Thus, antioxidants reverse superoxide-induced mito chondrial swelling and lipid peroxidation in vitro.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1007529622874
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    facet.materialart.
    Unknown
    Liquid to hexatic to crystalline order in Langmuir-Blodgett films (1995)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1995-07-07
    Description: Atomic force microscope images of zinc arachidate (ZnA2) Langmuir-Blodgett films show that three- and five-layer films are "hexatic," with long-range bond-orientational order and short-range positional correlations of three to five lattice repeats. The monolayer in contact with the substrate is disordered. Films of seven or more layers of ZnA2 are crystalline. A population of dislocations, most likely originating at the substrate, disrupts the positional but not the orientational order of the lattice, leading to hexatic layers intermediate between crystal and liquid. The influence of the substrate propagates farther into ZnA2 films than into cadmium arachidate films because the molecular cohesion is much weaker in ZnA2 than in cadmium arachidate, as evidenced by a less dense molecular packing.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Viswanathan, R -- Madsen, L L -- Zasadzinski, J A -- Schwartz, D K -- GM47334/GM/NIGMS NIH HHS/ -- HL51177/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1995 Jul 7;269(5220):51-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemical Engineering, University of California, Santa Barbara 93106, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7604278" target="_blank"〉PubMed〈/a〉
    Keywords: Chemistry, Physical ; Crystallization ; *Eicosanoic Acids ; Fatty Acids, Unsaturated/*chemistry ; Fourier Analysis ; *Membranes, Artificial ; Microscopy, Atomic Force ; Physicochemical Phenomena
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 6
    facet.materialart.
    Unknown
    Strained-layer van der Waals epitaxy in a Langmuir-Blodgett film (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-07-23
    Description: Atomic force microscope images of Langmuir-Blodgett films of lead and manganese fatty acid salts show that these monolayers have long-range order and are oriented with respect to the mica substrate, although the lattice symmetries of the monolayers and substrate are dramatically different. The surface lattice of sequentially thicker films evolves toward the bulk structure while retaining the substrate alignment. This behavior is in distinct contrast to films of cadmium fatty acid salts on mica, or all films on amorphous silicon oxide, in which the monolayer structure is disordered and a three-layer-thick film displays the bulk structure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Viswanathan, R -- Zasadzinski, J A -- Schwartz, D K -- GM 47334/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1993 Jul 23;261(5120):449-52.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemical and Nuclear Engineering, University of California, Santa Barbara 93106.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8392751" target="_blank"〉PubMed〈/a〉
    Keywords: Adsorption ; Aluminum Silicates ; Barium/chemistry ; Cadmium/chemistry ; Chemistry, Physical ; Crystallization ; Eicosanoic Acids/chemistry ; Fatty Acids/*chemistry ; Lead/chemistry ; Manganese/chemistry ; *Membranes, Artificial ; Physicochemical Phenomena ; Silicon Dioxide ; Stearic Acids/chemistry
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 7
    facet.materialart.
    Unknown
    Langmuir-Blodgett films (1994)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1994-03-25
    Description: The controlled transfer of organized monolayers of amphiphilic molecules from the airwater interface to a solid substrate was the first molecular-scale technology for the creation of new materials. However, the potential benefits of the technology envisioned by Langmuir and Blodgett in the 1930s have yet to be fully realized. Problems of reproducibility and defects and the lack of basic understanding of the packing of complex molecules in thin films have continued to thwart practical applications of Langmuir-Blodgett films and devices made from such films. However, modern high-resolution x-ray diffraction and scanning probe microscopy have proven to be ideal tools to resolve many of the basic questions involving thin organic films. Here, studies are presented of molecular order and organization in thin films of fatty acid salts, the prototypical system of Katharine Blodgett. Even these relatively simple systems present liquid, hexatic, and crystalline order; van der Waals and strained layer epitaxy on various substrates; wide variations in crystal symmetry and interfacial area with counterions; modulated superstructures; and coexisting lattice structures. The wide variety of possible structures presents both a challenge and an opportunity for future molecular design of organic thin-film devices.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zasadzinski, J A -- Viswanathan, R -- Madsen, L -- Garnaes, J -- Schwartz, D K -- GM 47334/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1994 Mar 25;263(5154):1726-33.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemical and Nuclear Engineering, University of California, Santa Barbara 93106.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8134836" target="_blank"〉PubMed〈/a〉
    Keywords: *Chemistry, Physical ; Lipids/*chemistry ; Membranes, Artificial ; Molecular Structure ; Physicochemical Phenomena ; Polymers/*chemistry ; Proteins/*chemistry
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...