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Drug transport across the blood-brain barrier (1993)

Bree, J. B. M. M. ; Boer, A. G. ; Danhof, M. ; [et al.]

Springer

Pharmacy world & science 15 (1993), S. 2-9

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ISSN: 1573-739X

Keywords: Biological transport ; Blood-brain barrier ; Cell membrane permeability ; Cerebrospinal fluid ; Peptides ; Prodrugs ; Proteins

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology

Notes: Abstract This is the third part of a review on the transport of drugs across the blood-brain barrier. In the first two parts, the anatomical and physiological aspects and the various techniques that can be used to study blood-brain transport have been discussed and reviewed. This third part focuses specifically on the mechanisms that are involved in drug transport across the blood-brain barrier. In addition, the opportunities to improve drug transport into the brain will be reviewed. Emphasis is on the transport of peptides.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02116163

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