ISSN:
0899-0042
Keywords:
enantiomers
;
countercurrent gas-liquid chromatography
;
preparative separation
;
amino acid derivatives
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Preparative separation of derivatives of amino acid enantiomers was carried out by a countercurrent gas-liquid chromatography (CCGLC) with chiral liquid phases, N-stearoyl-L-valine tert-butylamide and/or N-stearoyl-L-leucine tert-butylamide. In order to make effective use of these phases and also to lower the viscosity, Apiezon C was added as diluent. Through a repeated operation of a temperature gradient, purities more than 99% of leucine and α-amino butyric acid derivatives were proved to be obtained. © 1993 Wiley-Liss, Inc.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chir.530050411
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