ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • NMR software  (1)
  • Organic Chemistry  (1)
  • spiro-Cyclization  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Cocon: From NMR Correlation Data to Molecular Constitutions (1997)
    Springer
    Journal of molecular modeling 3 (1997), S. 364-368 
    Details
    ISSN: 0948-5023
    Keywords: Keywords: Computer-assisted structure elucidation ; Constitutional analysis ; HMBC ; ADEQUATE ; NMR software
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The constitutional assignment of natural products by NMR spectroscopy is usually based on 2D NMR experiments like COSY, HSQC, and HMBC. In this paper, the resulting connectivity information is used as input for the new structure generating program Cocon which both improves and dramatically accelerates the process of constitutional assignment. Cocon allows to quantify the value of connectivity information (2D NMR correlation data) for structure elucidation problems. Applying Cocon, it is systematically evaluated to which degree the NMR experiments COSY, 1H,13C-HMBC and 1,1-ADEQUATE constrain the number of constitutions compatible with the data sets of two secondary metabolites from marine sponges.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s008940050052
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Synthesis of rac-Midpacamide and the spiro-Cyclization of Its Precursor (1997)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1997 (1997), S. 1525-1528 
    Details
    ISSN: 0947-3440
    Keywords: Alkaloids ; Biomimetic synthesis ; spiro-Cyclization ; Marine sponges ; Natural products ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The alkylidene hydantoin 8 was synthesized as an analogue of the marine natural product oroidin (1) by employing a Horner-Wadsworth-Emmons reaction. Treatment of 8 with bromine in acetic acid induced a biomimetic spiro-cyclization forming the ACD ring system of dibromophakellin (2) in one step. rac-Midpacamide (10) was obtained from the same precursor through a chemoselective, ruthenium-catalyzed hydrogenation leaving the brominated pyrrole moiety intact.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.199719970731
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...