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  • Virology.  (2)
  • Molecular biology.  (1)
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  • 1
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Virology. ; Pharmacology. ; Biology Technique. ; Internal medicine. ; Virology. ; Pharmacology. ; Biological Techniques. ; Internal Medicine.
    Description / Table of Contents: Chapter 1 Hepatitis E Virus -- Chapter 2 Characteristics and Functions of HEV Proteins -- Chapter 3 Epidemiology of Hepatitis E -- Chapter 4 Hepatitis E as a Zoonosis -- Chapter 5 Genetic Evolution of Hepatitis E Virus -- Chapter 6 Transmission of Hepatitis E Virus -- Chapter 7 Immunobiology and Host Response to HEV -- Chapter 8 Cell Culture for hepatitis E virus -- Chapter 9 Stem Cell and organoid culture for hepatitis E virus -- Chapter 10 Lifecycle of hepatitis E Virus -- Chapter 11 Morphogenesis of Hepatitis E Virus -- Chapter 12 Animal Models for Hepatitis E Virus -- Chapter 13 Clinical Manifestations of Hepatitis E -- Chapter 14 Laboratory Diagnosis of HEV Infection -- Chapter 15 Treatment of Hepatitis E -- Chapter 16 Prophylactic Hepatitis E Vaccine -- Chapter 17 Puzzles for hepatitis E virus.
    Abstract: This book systematically and comprehensively discusses the biological, epidemiological, and clinical characteristics of the hepatitis E virus (HEV). It presents current knowledge of HEV and explores experimental methods, treatment, and prevention of HEV. First identified in the 1980s and cloned in 1990, HEV is the causative agent of hepatitis E, which mainly occurs in developing regions, such as Southeast Asia, the Middle East, and Africa, and significantly affects the health of the people in these areas. It is estimated that a third of the world’s population has been infected with HEV, which is transmitted via the fecal-oral route and can infect both humans and animals. In the second edition, new chapters are added to demonstrate the lifecycle, morphogenesis, and stem cell culture of hepatitis E virus. Although research on hepatitis E virus has made progress recently, there are still some problems that have not been solved. Those problems are discussed in this edition, which would be helpful for researchers to understand the problems on hepatitis E virus that they have faced. Meanwhile, the epidemiology, transmission, genetic evolution, animal models, treatment, and others in the related chapters of the first version were also updated according to the most recent research progress. The book provides an overview of HEV from benchside to bedside. It is a valuable resource for researchers in the field and those in the pharmaceutical industry developing HEV vaccines, as well as physicians involved in identifying and treating those infected with the virus.
    Type of Medium: Online Resource
    Pages: XII, 256 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789819913046
    Series Statement: Advances in Experimental Medicine and Biology, 1417
    DDC: 579.2
    Language: English
    Location Call Number Expected Availability
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  • 2
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Immunology. ; Virology. ; Molecular biology. ; Immunology. ; Virology. ; Molecular Biology.
    Description / Table of Contents: Chapter 1. Pseudotyped Viruses -- Chapter 2. Assays based on Pseudotyped Viruses -- Chapter 3. Application of Pseudotyped Viruses -- Chapter 4. Pseudotyped Viruses for Retroviruses -- Chapter 5. Pseudotyped Virus for Papillomavirus -- Chapter 6. Pseudotyped Viruses for Marburgvirus and Ebolavirus -- Chapter 7. Pseudotyped Viruses for Coronaviruses -- Chapter 8. Pseudotyped Viruses for Influenza -- Chapter 9. Pseudotyped Virus Systems for Studies of Henipavirus -- Chapter 10. Pseudotyped Viruses for lyssavirus -- Chapter 11. Pseudotyped Viruses for Enterovirus -- Chapter 12. Pseudotyped Viruses for Orthohantavirus -- Chapter 13. Pseudotyped Viruses for Phlebovirus -- Chapter 14. Pseudotyped Virus for Bandavirus -- Chapter 15. Pseudotyped Viruses for Mammarenavirus -- Chapter 16. Pseudotyped Viruses for the Alphavirus -- Chikungunya Virus -- Chapter 17. Pseudotyped Virus for Flaviviridae -- Chapter 18. Replicating-competent VSV-vectored Pseudotyped Viruses.
    Abstract: This book intends to report the new progress of pseudotyped viruses, including the construction of pseudotyped viruses with different strategies or vectors for most important viruses. Especially for emerging viruses, optimization of the condition and parameters for assay development based on the pseudotyped viruses and widely application as surrogate of authentic virus to study the biological functions of virus, detection of neutralizing antibody, screening viral entry inhibiters, and others. It includes most pseudotyped viruses that have the protein of the target virus on the surface of the parent virus with incomplete genome. The book is likely to be of interest to all researchers in the field of virology, vaccine, and anti-viral drug development and evaluation.
    Type of Medium: Online Resource
    Pages: XIII, 348 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819901135
    Series Statement: Advances in Experimental Medicine and Biology, 1407
    DDC: 571.96
    Language: English
    Location Call Number Expected Availability
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