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  • 1
    Publication Date: 1982-08-20
    Description: Fasting lowers blood pressure to a greater extent in spontaneously hypertensive rats than in normotensive rats. While fasting reduced cardiac sympathetic activity to an equivalent extent in both groups of animals, only in the hypertensive rats did fasting elicit an opiate-mediated vasodepressor response that was independent of sympathetic withdrawal. Both sympathetic nervous system suppression and endogenous opiate activation, therefore, may contribute to the hypotensive effect of fasting in the spontaneously hypertensive rat.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Einhorn, D -- Young, J B -- Landberg, L -- AM 20378/AM/NIADDK NIH HHS/ -- HL 24084/HL/NHLBI NIH HHS/ -- RR 76/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1982 Aug 20;217(4561):727-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7100917" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Blood Pressure/drug effects ; Endorphins/*physiology ; *Fasting ; Hypertension/physiopathology ; Male ; Myocardium/metabolism ; Naltrexone/pharmacology ; Norepinephrine/metabolism ; Rats ; Rats, Inbred Strains ; Sympathetic Nervous System/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 1982-01-08
    Description: Sympathetic nervous system activity was assessed in experimental and control subjects who were exposed to graded orthostatic and isometric stress during monthly hospital visits. After the first session, the experimental subjects practiced a technique that elicited the relaxation response. Their concentrations of plasma norepinephrine during subsequent graded stresses were significantly higher. No such changes were noted in the control group. These results were than replicated in the control group in a crossover experiment. The groups did not differ in their heart rate and blood pressure responses. These observations are consistent with reduced norepinephrine end-organ responsivity after regular elicitation of the relaxation response.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hoffman, J W -- Benson, H -- Arns, P A -- Stainbrook, G L -- Landsberg, G L -- Young, J B -- Gill, A -- HL-07374/HL/NHLBI NIH HHS/ -- HL-22727/HL/NHLBI NIH HHS/ -- HL-24084/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1982 Jan 8;215(4529):190-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7031901" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Blood Pressure ; Female ; Heart Rate ; Humans ; Male ; *Muscle Contraction ; *Muscle Relaxation ; Norepinephrine/blood ; *Relaxation Therapy ; Stress, Physiological/physiopathology ; Sympathetic Nervous System/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
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