ISSN:
1615-6102
Keywords:
Plasma membrane redox
;
Ehrlich ascites tumour cell
;
MCF-7 human breast cancer cell
;
MDA-MB231 human breast cancer cell
;
Glycolysis
;
Lactate
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Plasma membrane redox systems seem to play a role in the control of cell growth. In fact, we have found that in mammary tumour cell lines the increase in the proliferation rate is accompanied by a decrease in the plasma membrane redox activity. The oxygen consumption rates, the glycolytic fluxes and other bioenergetic parameters have been studied in two cell strains of Ehrlich ascites tumour with different proliferation rates. In the more proliferative Ehrlich cell strain, the decrease in plasma membrane redox system activity is accompanied by decreased oxygen consumption and glycolytic flux and to a generally less energised status.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01279307
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