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The pattern of density dependent growth inhibition in murine fibroblasts (1975)

Canagaratna, Mary C. P. ; Riley, P. A.

New York, NY [u.a.] : Wiley-Blackwell

Journal of Cellular Physiology 85 (1975), S. 271-281

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ISSN: 0021-9541

Keywords: Life and Medical Sciences ; Cell & Developmental Biology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: Observations on the pattern of nuclear incorporation of 3H-TdR in long term (8-day) and short term (3-day) 3T3 cultures with local cell densities between 0.2 × 104 and 6.2 × 104 cells/cm2 are reported. Contrary to a number of previous studies our observations indicate that density dependent inhibition is exhibited in relatively sparse cultures, commencing at 0.5 × 104 cells/cm2. Various possible mechanisms which could have caused the observed pattern of density-dependent regression in labelling index are discussed.

Additional Material: 5 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jcp.1040850214

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