ISSN:
0021-9541
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
The rate of synthesis of different hemoglobin (Hb) species - embryonic, primitive, definitive, and adult - in the circulating red cells of the chick embryo have been measured. On the fifth day of chick embryogenesis, there is a marked decrease in the capability of these red cells to synthesize Hb. The rates of synthesis of embryonic and primitive Hb decrease markedly compared to that of definitive and adult Hb. On the fourth day of embryogenesis nucleic acid synthesis drops sharply in these cells. These decreases in metabolic activity preceed the disappearance of the primitive erythrocyte from the chick embryo circulation. It appears that the primitive cell line is specifically shut off with respect to its metabolic activities and possibly destroyed at this time.
Additional Material:
6 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jcp.1040790113
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