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Neutral amino acid transport during the cell cycle of cultured human lymphocytes (1981)

Glassy, Mark C. ; Furlong, Clement E.

New York, NY [u.a.] : Wiley-Blackwell

Journal of Cellular Physiology 107 (1981), S. 69-74

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ISSN: 0021-9541

Keywords: Life and Medical Sciences ; Cell & Developmental Biology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: Neutral amino acid (isoleucine, leucine, and valine) transport was monitored in synchronous populations of WIL-2 cells, a diploid human lymphoblastoid B cell line. Cells were synchronized by either the double thymidine block technique or by density-dependent arrest in G1. Cells synchronized by these methods showed up to a 66% decrease in amino acid transport upon progressing from the early S phase through the G2 and M phases with a concomitant increase in transport during the G1 phase. The lowest activities of amino acid transport in synchronized cells were observed during the G2 and M phases.

Additional Material: 6 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jcp.1041070109

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