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Possible role of fibronectin in malignancy (1979)

Chen, Lan Bo ; Summerhayes, Ian ; Hsieh, Philip ; [et al.]

New York, N.Y. : Wiley-Blackwell

Journal of Supramolecular Structure 12 (1979), S. 139-150

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ISSN: 0091-7419

Keywords: fibronectin ; tumor ; malignancy ; cell shape ; hormone ; embryogenesis ; Life Sciences ; Molecular Cell Biology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Chemistry and Pharmacology , Medicine

Notes: Frozen sections of tumors induced by injecting virally transformed cells into animals were stained for fibronectin by immunofluorescence. Many tumor cell lines do not express fibronectin in tumors in situ even though some of them express fibronection in culture. Cell shape and hormones appear to influence the expression of fibronectin in culture; however, it is nuclear how fibronection expression is regulated in vivo.

Additional Material: 5 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jss.400120111

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