ISSN:
1434-4475
Keywords:
Human big gastrin I
;
Leu32-human big gastrin I
;
Synthetic peptide hormones
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The preparation of the pure tetratriacontapeptide amide 〈Glu-Leu-Gly-Pro-Gln-Gly-His-Pro-Ser-Leu-Val-Ala-Asp-Pro-Ser-Lys-Lys-Gln-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2 (human big gastrin I) and the analogue Leu32-human big gastrin I from the crude synthetic materials obtained after deblocking of the overall protected tetratriacontapeptide amide derivatives by means of trifluoroacetic acid is described. The criteria for homogeneity obtained by chromatographic, electrophoretic, enzymatic and spectroscopic methods are reported.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00938723
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