ISSN:
1432-1432
Keywords:
THE-1 sequences
;
Transposon-like human elements
;
LTR
;
MstII
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract A THE-1 sequence in intron 7 of the human dystrophin gene has been found to represent a new subfamily of THE-1 elements. The sequence is closely related to the MstII family of repetitive sequences and is more like single-copy sequences found in the galago genome than any other THE-1 sequence previously reported. This new THE-1 sequence has been compared with two other complete THE-1 sequences and three related long-terminal repeat elements that we have previously found in intron 7 of the dystrophin gene, and with members of the same family from elsewhere in the primate genome. Parsimony and deletion analysis show that the cluster of THE-1 sequences in intron 7 of the dystrophin gene has arisen from at least three individual insertion events, rather than from the insertion and duplication of a single progenitor sequence.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00167108
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