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  • LIFE SCIENCES (GENERAL)  (2)
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  • 1
    Publication Date: 2019-07-12
    Description: The effect of progressive treadmill exercise on oxidative capacity in three specific diaphragm muscle fiber types and on the capillary density of known fiber types was investigated in young (5 month) and senescent (23 months or older) rats. All animals were trained for 1 hr/day, 5 days weekly, for 10 weeks. Measurements of succinate dehydrogenase activity showed significant increases in all three fiber types in both the young and the senescent trained animals, compared with their sedentary controls. Fiber size and capillary density were not affected by exercise or age. The results demonstrate that the senescent costal diaphragm maintains its ability to adapt to an increased metabolic demand brought about by locomotor exercises.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Journal of Applied Physiology (ISSN 8750-7587); 72; 4 Ap; 1506-151
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  • 2
    Publication Date: 2019-07-12
    Description: The effects of aging and exercise training on the myosin heavy chain (MHC) composition were determined in both the costal and crural diaphragm regions of female Fischer 344 rats. Treadmill running at 75 percent maximal oxygen consumption resulted in similar increases in plantaris muscle citrate synthase activity in both young (5 mo) and old (23mo) trained animals (P less than 0.05). It was found that the ratio of fast to slow MHC was significantly higher (P less than 0.005) in the crural compared with costal diaphragm region in both age groups. A significant age-related increase in persentage of slow MHC was observed in both diaphragm regions. The relative proportion of slow MHC in either costal or crural region was not changed by exercise training.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Journal of Applied Physiology (ISSN 8750-7587); 73; 4; p. 1282-1286.
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