Electronic Resource
Springer
Journal of molecular evolution
43 (1996), S. 165-169
ISSN:
1432-1432
Keywords:
Key words: RNA secondary structure — Neutral Evolution — Adaptive evolution — Genotype-phenotype relation — Sequence space — Fitness landscape
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract. RNA secondary-structure folding algorithms predict the existence of connected networks of RNA sequences with identical secondary structures. Fitness landscapes that are based on the mapping between RNA sequence and RNA secondary structure hence have many neutral paths. A neutral walk on these fitness landscapes gives access to a virtually unlimited number of secondary structures that are a single point mutation from the neutral path. This shows that neutral evolution explores phenotype space and can play a role in adaptation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/PL00006074
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