ISSN:
0170-2041
Keywords:
Juvenoids
;
Oxime ethers
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Two racemic juvenoids 5 and 6 and their optical isomers 10, 11, 17 and 18 having chiral centres in the aliphatic side chain were synthetized. The second chiral centre in the molecules remained racemic in all derivatives prepared. The absolute configurations of the optically active centres of the enantiomers were determined on the basis of the 1H-NMR spectral evaluation of the diastereoisomeric MTPA esters 12, 13, 19 and 20 derived from the intermediate alcohols 8 and 15. The optical purity was established by an HPLC analysis of the corresponding MTPA esters. The 1H-NMR spectra of all compounds as well as the CD spectra of all chiral isomers were measured and discussed.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1990199001159
Permalink
